USB can send large packets of information, such as real-time audio and very detailed controller information.MIDI can only send and receive very small packets of data (note on/off - prog change - etc) basically just a set of instructions about what note to play and how i.e.MIDI connects via a 5 pin connection, whereas a USB connects via, well, a USB! The major difference between the two types of controller is the way they connect.The differences between USB and MIDI controllers
Well, let me break it down for you and provide some examples of controllers and keyboards and highlight what you might be using them for to give you a better understanding. So what are the major differences between USB and MIDI, I hear you ask? However, when you want to get a little more serious about creating your perfect sound, you’ll notice that the differences between USB and MIDI controllers becomes quite apparent, especially when it comes to compatibility. If you’re creating electronic music of any kind, chances are you’ll come across a USB and a MIDI keyboard or controller.